Use Synthace to plan and run experiments on dispensers that need several input and output plates, generating as many execution files as necessary from a single workflow!
If you are looking to run a complex DOE with a lot of components, spanning over several assay plates, or are looking to scale your sample prep at a higher throughput, build your workflow and Synthace will generate the necessary number of instruction files.
When designing a DoE, only split runs across workflows if you need to block by a factor. If your design generates more runs than wells on your output plate, Synthace will automatically add additional output plates.
In Simulation Details, you can find all the plates you will need in Input & Output Plate areas, and move through the timeline to see how they will be used throughout the run. View highlighted manual intervention points in Simulation Preview for run interruptions like plate changes or prompts. These areas may look slightly different for the different dispenser models.
On the Execution page, download all the instruction files needed for a stage, and view which input and output plates are required for each instruction file at a glance. Review a printable summary of all plates needed for a stage in Execution Details using the option to view plate contents on hover. The way plates are grouped per instruction file and the number of files generated depend on the capabilities of each device native software. See the documentation for each dispenser in our Help Center for more details.
Having trouble keeping track of all the plates you need? Not a problem! Hover over a plate to review the contents of each individual plate needed for each part of the stage. For plates that are used for several instruction files, Synthace will show the state of the plate at the start of the corresponding part of the run.
Note: To minimize the number of plate movements, ensure that liquids are added to all destination wells in the same order by specifying "Addition Mode" = "Liquid Order" when building your workflow. Synthace will then plan the experiment in a way that minimizes the necessary plate swaps, accounts for the number of input and output plates needed, and splits the execution into as many device instruction files as necessary. To learn more about controlling the addition order of your liquids, click here.
