Yes. As a publisher or author, you’re responsible for ensuring your EPUBs meet accessibility standards. This includes:
Adding alt text to meaningful images
Using clear headings and logical navigation
Avoiding fixed layouts or excessive styling
Ensuring hyperlink text is descriptive—this includes adding alt text to ALL images used as hyperlinks
Keeping text reflowable and resizable
If your eBook doesn’t meet these standards, retailers may ask you to declare it as “Not Accessible.” PDF books are automatically categorized as not accessible.