Currently pregnant, nursing, or planning to become pregnant in the next year

Family or personal history of medullary thyroid cancer

Personal history of multiple endocrine neoplasia type 2 (MEN2)

Active eating disorder or history of eating disorder (bulimia, anorexia, etc.)

Currently being treated for cancer

Active drug or alcohol misuse

Suicidal thoughts or past attempts

Mental health disorders (bipolar disorder, anxiety disorder, schizophrenia, etc.)

Current or history of pancreatitis

Bariatric surgery (within the last 18 months)

Heart attack (within the last 12 months)

Heart failure

Organ transplant or immunosuppressive therapy

Severe gastrointestinal diseases such as gastroparesis and inflammatory bowel disease

Gallbladder disease

Kidney disease

Liver disease

Diabetic retinopathy

Insulin us

Atrial fibrillation (A-fib) or tachycardia