Related Questions:
It won't let me press the send button
The "send" button is a faded color
The send button is blocked
The link button won't click
Why are buttons blocked on an email?
Wont allow me to hit the send button
Answer:
When sending an email, there must be an email address in the 'to' field. If no Contact has been selected, or a Contact with no email address has been selected, you will not be able to send the email.