How It Works
Alcohol cravings develop due to a complicated series of reactions in the brain. If we simplify that process (as it is currently understood), it works something like this:
When a person drinks, their body releases opioid neuropeptides (endorphins) that make them feel good.[1] It also triggers the brain’s reward system, which uses dopamine and other neurotransmitters to “communicate” between a complex series of brain functions.[2] Over time, the reward system begins to recognize alcohol as something it should motivate you to consume. It adjusts accordingly, resulting in alcohol cravings that can lead to Alcohol Use Disorder (AUD).
Naltrexone is an opioid antagonist. It blocks neuroreceptors in the brain from receiving the endorphins that are released when one drinks alcohol.[3] As a result, naltrexone disrupts the process that caused alcohol cravings to develop. Over time, that disruption diminishes cravings. This makes naltrexone highly effective as a treatment for AUD. Additionally, it isn’t habit-forming, has few side effects, and is safe to take for long periods when taken appropriately.
Why We Use It
Programs that don’t use medication don’t account for a key aspect of AUD—it has severe effects on brain function. Over time, drinking can damage neurons and brain matter. It also alters how the brain releases neurotransmitters, which affect how one thinks and feels.[4] That’s why relapses are frequent in abstinence programs—AUD makes the brain accustomed to alcohol, and it reacts negatively when alcohol is removed. That’s why we use medication to counteract the effects of alcohol that cause the brain to crave it.
Naltrexone is an FDA-approved medication that suppresses the pleasurable effects of alcohol and leads to reduced alcohol consumption. Because it affects cravings at the level of the brain, abstinence isn’t required. Naltrexone can be used to control alcohol consumption indefinitely. That’s why LifeBac uses naltrexone—so each person gets to choose their end goal.
We create medication plans for each member of LifeBac and monitor their progress so they stay on track with the medication. That, combined with support from our LifeBac Guides, gives each individual a great chance to choose a new relationship with alcohol.
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