The main difference between the two methods of administration is bioavailability. In other words, your body absorbs more of the medication when administered through an IV.

Our clinicians use a starting dose of 5mg/kg of body weight. This is comparable to the 0.5mg/kg gold IV standard. The metric we use looks higher than the IV dosing because of the difference in bioavailability between sublingual ketamine and IV ketamine.

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