In general it is better to come off antidepressants when you are feeling well, but there are times when someone may wish to come off of antidepressants even while they are experiencing depression or anxiety. For example:
You feel that you get no benefit from the drug
You are experiencing adverse effects that you feel outweigh any helpful effects
Your antidepressant conflicts with another medicine or treatment
You decide you no longer wish to take the drug
It’s important to talk to your healthcare provider about the risks and benefits of stopping antidepressant treatment while still experiencing depression or anxiety, so you can have a plan in place to manage those symptoms.