Yes! This can be done using Automation.
To begin open the Interactivity of your design.
Select the More Information module followed by the Automation icon (the little wand).
Complete the automation as follows:
Event - select 'When Popup is Shown'.
Delay - enter the length of time that you would like the pop-up box to display for. For example, 10 seconds.
Action - select 'Close This Popup'.
The above example shows that the popup box will display for 10 seconds before automatically closing.