You will get notified once it is time to re-fill your pillbox and you can refill it at regular intervals in two different ways:
1. Put your medications in all the pillbox compartments. You will then receive an automatic notification that the pillbox has been re-filled. You can do this at any time and the pill box does not have to be empty of medications for it to work. If you take medicine twice a day, make sure that all your morning medicines are in the A-column (located on the inside of the compartments) and all evening medicines are in the B-column.
2. You can also use the refilling flow in the app by going to the Pillbox tab. Press "Refill" and follow the instructions in which compartments to put which medicines.