Programmatic demand will bid on your inventory if you have an up-to-date Ads.txt file in place. You can learn more about implementing Ads.txt here.

When receiving traffic, you may see redirects from AppNexus or Bidswitch as opposed to 

To enable or disable RTB, reach out to your Publishing Representative, Account Manager, or, who can do this for you. Enabling programmatic demand opens up your inventory to more advertisers which increases the competition for placement on your widgets.

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