SafeGard physicians commonly prescribe one of two medications to prevent malaria: atovaquone-proguanil (Malarone) or doxycycline.
Both are effective and widely recommended as malaria prophylaxis, but they differ in duration, side effects, and cost.
Malarone (atovaquone-proguanil)
Generally preferred for most travelers.
Shorter course: Take 1–2 days before travel and must continue for 7 days after leaving the malaria area.
Fewer side effects: Usually well tolerated, with minimal stomach upset.
Higher cost: Often more expensive than doxycycline, especially for long trips.
Doxycycline
Effective and lower-cost alternative for many travelers.
Longer course: Take 1–2 days before travel and must continue for 4 weeks after leaving the malaria area.
May cause sun sensitivity, heartburn, or mild gastrointestinal upset.
Which one should I choose?
For most travelers, Malarone is recommended because it’s a shorter course and easier to tolerate.
However, doxycycline may be preferred for travelers on longer trips or those seeking a lower-cost option.
Your pharmacist will review your prescriptions with you during your appointment and can help confirm which option is most appropriate for your travel plans and budget.
Disclaimer: This information is provided for general educational purposes only and is not a substitute for personalized medical advice. Always follow the guidance of your physician or pharmacist.