Commercial Driver License Medical Self-Certification Affidavits and Medical Cards can be done online.
If you are the CDL holder, you can update your CDL DOT Medical Card or Self-Certification status using the online form here at https://oklahoma.gov/service/sokonline/online-dot-medical-update.html
If you are a doctor or employer submitting an updated DOT Medical Card or Self-Certification form on behalf of the CDL driver, you can submit the form via email or mail.
Email - mec@service.ok.gov
Mail - Service Oklahoma
P.O. Box 11415
Oklahoma City, OK 73136
Attn: CDL Help Desk
For full details on CDL Medical Certification Requirements: Here