You can quickly swap pairings (players 1&2 and 3&4 in each pairing group) while editing pairings. To do this:
Go to Rounds > Edit Existing Pairings.
Click "Swap Pairs".
Click the first pair of players you would like to swap then click the second pair of players. You will see the pairs switch places and starting hole/tee time in the pairings. (Note: swapping pairs or players will change the swapped player's GGIDs if you are using live scoring.)
Save the pairings.
See the sequence below: