What Melanotan II Is
Melanotan II is a melanocortin peptide that stimulates the body’s melanin production pathways, which may lead to gradual skin pigmentation and increased UV tolerance.
Reconstitution
• Add 5.0 mL bacteriostatic water → final concentration 2.0 mg/mL
• This dilution makes microgram dosing easier to measure.
Typical Daily Dose Range
• 0.10 mg – 0.50 mg daily
• Gradual escalation is commonly used:
• 0.10 mg → 0.25 mg → 0.50 mg
• Most adults do not exceed 0.50–1.0 mg daily
Syringe Math
• At 2.0 mg/mL → 1 unit = 0.01 mL ≈ 20 mcg
Storage
Lyophilized:
• Store frozen at −20 °C
Reconstituted:
• Refrigerate at 2–8 °C
• Use within 2–4 weeks
Daily Dosing Schedule
Phase | Daily Dose | Syringe Units | Volume |
Days 1–3 | 100 mcg | 5 units | 0.05 mL |
Days 4–7 | 250 mcg | 12.5 units | 0.125 mL |
Day 8+ | 500 mcg | 25 units | 0.25 mL |
Frequency: Once daily, subcutaneous
Reason for escalation: gradual titration may help reduce early side effects such as nausea or flushing.
Supply Planning
MT-2 10mg Vials
8 weeks: ~3 vials
12 weeks: ~5 vials
16 weeks: ~6 vials
Syringes
1 per day
8 weeks → 56
12 weeks → 84
16 weeks → 112
Bacteriostatic Water (5 mL per vial)
8 weeks → 15 mL
12 weeks → 25 mL
16 weeks → 30 mL
Alcohol Pads
2 per day
8 weeks → 112
12 weeks → 168
16 weeks → 224
Protocol Overview
Goal:
Stimulate melanin production and gradual pigmentation through melanocortin receptor activation.
Structure:
• Once-daily injections
• Gradual escalation → 0.10 mg → 0.25 mg → 0.50 mg
Storage Instructions
Lyophilized:
• Store frozen at −20 °C
Reconstituted:
• Refrigerate at 2–8 °C
• Use within 2–4 weeks
Important Notes (Use + Safety)
Always use a new sterile syringe
Rotate injection sites (abdomen, thigh, arms)
Inject slowly to reduce discomfort
Track daily doses & any side effects
Watch for mole changes—seek derm evaluation if anything looks new or different
Hydrate well to reduce nausea and flushing
Avoid >2 mg/day
How Melanotan II Works
Melanotan II is an analog of α-MSH (alpha-melanocyte-stimulating hormone).
It activates:
MC1R → boosts melanin production → tanning
MC4R → responsible for libido/erectile effects
Tanning typically begins after 5–10 doses.
Effects accumulate gradually over 4–8 weeks of daily use.
Potential Benefits
Increased tanning, even with little or no UV exposure
Faster pigment buildup with small UV exposure
Strong libido/erectile response in many men
Long-lasting pigmentation with weekly maintenance
Common Side Effects
Nausea (most common; dose-dependent)
Facial flushing
Light fatigue
Injection-site redness
Spontaneous erections (male)
Serious Risks (Rare but Important)
Toxicity at high doses (>2 mg/day)
Rhabdomyolysis reported at 6 mg
Mole darkening or changes
Transient elevated HR or BP at high doses
Not FDA-approved (regulatory risk)
A known side effect is erectile activity due to MC4R activation.
Lifestyle Tips (For Best + Safest Results)
Use sunscreen to reduce skin cancer risk
Stay hydrated, especially early in loading phase
Monitor moles / skin changes regularly
Use minimal UV exposure if tanning faster is desired
Keep doses low and consistent—more is not better
Injection Technique (Clean, Safe, Simple)
Clean hands + work on a clean surface
Swab vial top + injection site (let dry)
Pinch 1" of skin
Insert needle at 45–90°
Inject slowly
Remove needle, apply light pressure
Rotate sites daily
Dispose syringe in sharps container
Disclaimer:
All peptide products sold on this website are for research, laboratory, and educational purposes only. They are not approved by the FDA or Health Canada, are not intended for human consumption, and should not be used for medical, cosmetic, or therapeutic purposes unless specifically prescribed by a licensed healthcare professional.
The information provided on this site is for informational and educational purposes only and does not constitute medical advice. Product descriptions, protocols, or references are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before beginning any new protocol, supplement, or treatment.
By purchasing from this website, you acknowledge and agree to use these products responsibly and in accordance with all applicable laws and guidelines.