What GHK-Cu Is
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding peptide found in human plasma and tissues.
In research settings, it has been studied for its potential role in tissue repair, collagen production, skin regeneration, and anti-inflammatory signaling.
It may influence gene expression related to healing pathways, antioxidant defense, and cellular renewal, which is why it’s widely explored in dermatology and regenerative research.
Reconstitution
• Add 2.5 mL bacteriostatic water → final concentration 40 mg/mL
• This dilution makes 0.5–2 mg dosing easy to measure
Typical Daily Dose Range
• 0.5–2 mg once daily
• Conservative protocols often start lower and escalate gradually
• Example escalation: 0.5 mg → 1 mg → 2 mg
• Typical research cycles run 4–8 weeks
Syringe Math
• At 40 mg/mL → 1 unit = 0.01 mL ≈ 0.4 mg (400 mcg) on a U-100 insulin syringe
Storage
Lyophilized (freeze-dried)
• Store frozen at −20 °C (−4 °F)
Reconstituted
• Refrigerate at 2–8 °C (35.6–46.4 °F)
• Use within 30–45 days
Daily Dosing Schedule (6-Week Example)
Phase | Daily Dose | Syringe Units | Volume |
Weeks 1–2 | 500 mcg (0.5 mg) | 1.25 units | 0.0125 mL |
Weeks 3–4 | 1,000 mcg (1 mg) | 2.5 units | 0.025 mL |
Weeks 5–6 | 2,000–2,500 mcg (2–2.5 mg) | 5–6.25 units | 0.05–0.0625 mL |
Optional: If your syringe has no half marks, round to the nearest whole unit.
Frequency: Once daily, subcutaneous
Duration: 6 weeks
Some individuals choose to take a short break between cycles depending on goals and response.
Daily doses may also be split into two smaller injections to help build tolerance or reduce effects such as flushing, warmth, or injection discomfort.
How to Reconstitute
Draw 2.5 mL bacteriostatic water
Inject slowly down the vial wall (prevents foaming)
Gently swirl or roll — never shake
Label the vial with the reconstitution date
Refrigerate at 2–8 °C
Why 2.5 mL?
This dilution provides a clean 40 mg/mL concentration, allowing simple dosing math across most research ranges.
Example:
1.25 units = 0.5 mg
2.5 units = 1 mg
5 units = 2 mg
Supply Planning
GHK-Cu 100 mg Vials
• 6-week protocol: ~1 vial
• 12-week protocol: ~2 vials
• 24-week protocol: ~4 vials
Syringes
• 1 per day
• 6 weeks: 42
• 12 weeks: 84
Bacteriostatic Water
(2.5 mL per vial)
• 6 weeks: 2.5 mL
• 12 weeks: 5 mL
Alcohol Pads
• 2 per day
• 6 weeks: 84
• 12 weeks: 168
Protocol Overview
Goal:
Support research into skin regeneration, tissue repair, and collagen signaling pathways.
Structure:
• Daily subcutaneous injections
• Gradual escalation 0.5 mg → 1 mg → 2 mg
• Typical cycles 4–8 weeks
Reconstitution:
2.5 mL → 40 mg/mL
Storage:
Freeze lyophilized; refrigerate reconstituted.
Storage Instructions (Keep It Stable)
Lyophilized
• Store frozen at −20 °C or colder
• Protect from moisture and light
Reconstituted
• Refrigerate at 2–8 °C
• Use within 30–45 days
Handling Tips
• Allow frozen vials to reach room temperature before opening
• Avoid heat or direct sunlight
• Minimize repeated temperature fluctuations
Important Practical Notes
• Stay consistent — inject at roughly the same time each day
• Start low to assess individual tolerance
• Use a new sterile syringe each injection
• Rotate injection sites (abdomen, thighs, upper arms)
• Splitting doses may help reduce temporary flushing or warmth
How GHK-Cu Works (Quick Science Made Simple)
GHK-Cu functions as a signaling peptide that binds copper and helps regulate biological repair processes.
Research suggests it may influence:
• Collagen and elastin production
• Wound healing and tissue remodeling
• Anti-inflammatory pathways
• Antioxidant defense
• Gene expression linked to cellular repair
Because of these properties, GHK-Cu is widely studied in dermatology, regenerative biology, and aging research.
Potential Benefits & Side Effects
Potential Research Benefits
• Enhanced collagen synthesis
• Support for skin regeneration
• Improved tissue repair signaling
• Anti-inflammatory effects
Possible Side Effects
• Temporary warmth or flushing
• Mild injection-site irritation
• Occasional headache or nausea
• Rare sensitivity reactions
Most side effects are mild and dose-dependent.
Injection Technique (Simple & Safe)
Before injecting
• Wash hands
• Clean vial stopper
• Clean injection site
• Draw dose and remove air bubbles
How to inject
Pinch about 1 inch of skin
Insert needle at 90° (or 45° if lean)
Inject slowly
Remove needle straight out
Dispose in sharps container
After
• Refrigerate vial
• Rotate injection sites
• Monitor for redness or irritation
Disclaimer:
All peptide products sold on this website are for research, laboratory, and educational purposes only. They are not approved by the FDA or Health Canada, are not intended for human consumption, and should not be used for medical, cosmetic, or therapeutic purposes unless specifically prescribed by a licensed healthcare professional.
The information provided on this site is for informational and educational purposes only and does not constitute medical advice. Product descriptions, protocols, or references are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before beginning any new protocol, supplement, or treatment.
By purchasing from this website, you acknowledge and agree to use these products responsibly and in accordance with all applicable laws and guidelines.