What Tesamorelin + Ipamorelin + CJC-1295 Is
This blend combines three growth hormone–related peptides that act through complementary pathways to stimulate natural growth hormone (GH) signaling.
Tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH) that stimulates the pituitary gland to release GH.
CJC-1295 also targets the GHRH receptor and may help prolong GH signaling and pulsatility.
Ipamorelin activates the ghrelin receptor, which can stimulate GH release without significantly increasing cortisol or prolactin in many research settings.
Together, these peptides are often explored in research related to metabolism, recovery, body composition, and growth hormone regulation.
Reconstitution
• Add 3.0 mL bacteriostatic water → final concentration 4 mg/mL total peptide
Peptide concentration after mixing:
• Tesamorelin: 2 mg/mL
• Ipamorelin: 1 mg/mL
• CJC-1295: 1 mg/mL
This dilution allows 300–500 mcg doses to be measured easily.
Typical Daily Dose Range
• 300–500 mcg per injection
• Often administered once daily
• Some protocols may use 1–2 injections per day
• Conservative protocols typically start lower and increase gradually
• Example escalation: 300 mcg → 400 mcg → 500 mcg
• Typical research cycles run 8–12 weeks
Syringe Math
At 4 mg/mL concentration
• 1 unit = 0.01 mL ≈ 40 mcg total peptide on a U-100 insulin syringe
Approximate breakdown per unit:
• Tesamorelin: ~20 mcg
• Ipamorelin: ~10 mcg
• CJC-1295: ~10 mcg
Example doses:
Dose | Units | Volume |
300 mcg | 7–8 units | 0.07–0.08 mL |
400 mcg | 10 units | 0.10 mL |
500 mcg | 12–13 units | 0.12–0.13 mL |
Daily Dosing Schedule (Example Protocol)
Phase | Dose | Syringe Units | Volume |
Weeks 1–2 | 300 mcg | 7–8 units | 0.07–0.08 mL |
Weeks 3–8 | 400–500 mcg | 10–12 units | 0.10–0.12 mL |
Frequency: Once daily, subcutaneous.
Most commonly administered:
• Before bedtime
• In a fasted state
Gradual escalation may help support tolerability and natural growth hormone pulsatility.
How to Reconstitute
Draw 3.0 mL bacteriostatic water
Inject slowly down the vial wall (prevents foaming)
Gently swirl or roll — never shake
Label the vial with the reconstitution date
Refrigerate at 2–8 °C
Why 3.0 mL?
This dilution provides a clean 4 mg/mL concentration, allowing easy measurement across common dosing ranges.
Example:
8 units ≈ 320 mcg
10 units ≈ 400 mcg
12 units ≈ 480 mcg
Supply Planning
Tesamorelin / Ipamorelin / CJC-1295 (6mg : 3mg : 3mg)
Approximate usage:
Daily Dose | Duration |
300 mcg/day | ~40 days |
400 mcg/day | ~30 days |
500 mcg/day | ~24 days |
Syringes
• 1 per day
• 8 weeks: 56
• 12 weeks: 84
Bacteriostatic Water
(3 mL per vial)
• 1 vial: 3 mL
• 2 vials: 6 mL
Alcohol Pads
• 2 per injection
• 8 weeks: 112
• 12 weeks: 168
Protocol Overview
Goal:
Support research into growth hormone signaling, metabolism, and recovery pathways.
Structure:
• Daily subcutaneous injections
• Gradual escalation 300 mcg → 500 mcg
• Typical cycles 8–12 weeks
Reconstitution:
3.0 mL → 4 mg/mL
Storage:
Freeze lyophilized; refrigerate reconstituted.
Storage Instructions
Lyophilized
• Store frozen at −20 °C or colder
• Protect from moisture and light
Reconstituted
• Refrigerate at 2–8 °C
• Use within 30–45 days
Handling Tips
• Allow frozen vials to reach room temperature before opening
• Avoid heat or direct sunlight
• Minimize repeated temperature fluctuations
Important Practical Notes
• Stay consistent — inject at roughly the same time each day
• Starting lower may help assess individual tolerance
• Use a new sterile syringe for each injection
• Rotate injection sites (abdomen, thighs, upper arms)
• Many protocols prefer fasted injections to support GH signaling
How the Blend Works
The three peptides stimulate growth hormone release through complementary pathways.
Tesamorelin and CJC-1295 stimulate the GHRH receptor, encouraging the pituitary gland to release growth hormone.
Ipamorelin activates the ghrelin receptor, further promoting GH release while helping preserve natural hormonal balance.
Together, these peptides may help support:
• Natural GH pulsatility
• Fat metabolism
• Recovery signaling
• Sleep-related GH release
Potential Benefits & Side Effects
Potential Research Benefits
• Support for growth hormone signaling
• Improved recovery pathways
• Support for body composition research
• Enhanced metabolic signaling
Possible Side Effects
• Mild water retention
• Temporary flushing or warmth
• Mild headache
• Occasional injection-site irritation
Most side effects are dose-dependent and mild.
Injection Technique
Before injecting
• Wash hands
• Clean vial stopper
• Clean injection site
• Draw dose and remove air bubbles
How to inject
Pinch about 1 inch of skin
Insert needle at 90° (or 45° if lean)
Inject slowly
Remove needle straight out
Dispose in sharps container
After
• Refrigerate vial
• Rotate injection sites
• Monitor for redness or irritation
Disclaimer
All peptide products sold on this website are for research, laboratory, and educational purposes only. They are not approved by the FDA or Health Canada, are not intended for human consumption, and should not be used for medical, cosmetic, or therapeutic purposes unless specifically prescribed by a licensed healthcare professional.
The information provided on this site is for informational and educational purposes only and does not constitute medical advice. Product descriptions, protocols, or references are not intended to diagnose, treat, cure, or prevent any disease.
Always consult a qualified healthcare provider before beginning any new protocol, supplement, or treatment.
By purchasing from this website, you acknowledge and agree to use these products responsibly and in accordance with all applicable laws and guidelines.