Tesamorelin is a synthetic growth hormone–releasing hormone (GHRH) analog that stimulates the pituitary gland to release the body’s natural growth hormone.

In clinical studies, Tesamorelin has been researched for reducing visceral abdominal fat and improving metabolic markers, particularly in individuals with metabolic complications.

Rather than supplying growth hormone directly, Tesamorelin signals the body to produce its own, helping maintain natural hormone rhythms.

• Add 4.0 mL bacteriostatic water → final concentration 5.0 mg/mL

• This concentration keeps dosing math consistent across vial sizes

• 0.5–2 mg once daily (gradual escalation recommended)

• Conservative escalation → 0.5 mg → 1 mg → 1.5 mg → 2 mg

• Clinical trials most commonly used 2 mg daily

• At 5.0 mg/mL → 1 unit = 0.01 mL ≈ 50 mcg on a U-100 insulin syringe

Lyophilized (freeze-dried):

• Freeze at −20 °C (−4 °F)

Reconstituted:

• Refrigerate at 2–8 °C (35.6–46.4 °F)

• Use within 2–4 weeks

Frequency: Once daily, subcutaneous.

Timing: Often administered before bedtime to align with natural growth hormone release patterns.

Draw 4.0 mL bacteriostatic water

Inject slowly down the vial wall (prevents foaming)

Gently swirl or roll — never shake

Label with reconstitution date

Refrigerate (2–8 °C) and protect from light

Using 4.0 mL keeps the same 5 mg/mL concentration as the 10 mg vial, so syringe math stays identical across vial sizes.

This makes dosing simpler and easier to remember.

• 4-week protocol: ~1 vial

• 12-week protocol: ~3–4 vials

• 24-week protocol: ~7–8 vials

• 1 per day

• 4 weeks: 28

• 12 weeks: 84

• 24 weeks: 168

• 4 weeks: ~4 mL

• 12 weeks: ~16 mL

• 24 weeks: ~32 mL

• 2 per injection

• 4 weeks: 56

• 12 weeks: 168

• 24 weeks: 336

Support reduction of visceral abdominal fat, improved metabolic markers, and optimized growth hormone signaling.

• Once-daily injections

• Gradual escalation → 0.5 mg → 1 mg → 1.5 mg → 2 mg

• Clinical trials commonly used 2 mg daily

4.0 mL → 5.0 mg/mL for simple dosing math across vial sizes.

Freeze lyophilized; refrigerate reconstituted solution.

• Store frozen at −20 °C or colder

• Protect from moisture and light

• Refrigerate at 2–8 °C

• Use within 2–4 weeks

• Let frozen vials reach room temperature before opening

• Avoid heat or direct sunlight

• Minimize freeze–thaw cycles

• Aliquot if storing long-term

• Stay consistent — inject at the same time each day

• Evening injections are common due to natural nighttime GH release

• Use a new sterile syringe every time

• Rotate injection sites (abdomen, thighs, upper arms)

• Start lower (0.5–1 mg) if sensitivity occurs

Tesamorelin stimulates growth hormone release from the pituitary gland, which increases IGF-1 levels that regulate metabolism and fat utilization.

Growth hormone signaling supports:

Fat metabolism and fat breakdown

Lean body composition

Tissue recovery and metabolic function

In clinical studies:

Tesamorelin significantly reduced visceral abdominal fat

Participants showed improvements in lipid markers and waist circumference

Long-term studies demonstrated sustained reductions in trunk fat mass

• Reduction in visceral abdominal fat

• Improved metabolic markers

• Support for natural growth hormone production

• Daily dosing allows steady hormone signaling

• Mild water retention or swelling

• Joint stiffness or muscle discomfort

• Injection site redness or irritation

• Temporary tingling sensations

Most side effects reported in studies were mild and manageable.

Disclaimer:

All peptide products sold on this website are for research, laboratory, and educational purposes only. They are not approved by the FDA or Health Canada, are not intended for human consumption, and should not be used for medical, cosmetic, or therapeutic purposes unless specifically prescribed by a licensed healthcare professional.

The information provided on this site is for informational and educational purposes only and does not constitute medical advice. Product descriptions, protocols, or references are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before beginning any new protocol, supplement, or treatment.

By purchasing from this website, you acknowledge and agree to use these products responsibly and in accordance with all applicable laws and guidelines.