Different Dosages of NAD+ and Their Effects
Dr. Ross Grant's research on NAD+ (Nicotinamide Adenine Dinucleotide) highlights the significant role this molecule plays in cellular health, energy production, and DNA repair. Here are the insights into the different dosages and their effects:
Low Dose (100mg - 250mg):
Energy Boost: Low doses are effective for increasing cellular energy levels and combating fatigue. This dosage is often used for general wellness and minor cognitive improvements.
Mild Detoxification: Helps in mild detoxification processes, supporting liver function and overall metabolic health.
Medium Dose (250mg - 500mg):
Cognitive Enhancement: Medium doses have a more pronounced effect on cognitive functions, including memory and mental clarity. This is beneficial for individuals experiencing moderate cognitive decline or brain fog.
Metabolic Benefits: Improves metabolic processes, aiding in better nutrient absorption and utilization, which can help with weight management and energy metabolism.
High Dose (500mg - 1000mg):
Neuroprotection: High doses are used for neuroprotective effects, particularly in conditions like neurodegenerative diseases, Parkinson's, and Alzheimer’s. These dosages help in reducing neural inflammation and promoting brain health.
Detoxification and Recovery: Beneficial for individuals recovering from substance abuse, as it supports detoxification and recovery processes by enhancing cellular repair mechanisms.
Anti-Aging: High doses also have anti-aging benefits, supporting cellular repair, and reducing oxidative stress and DNA damage.
NAD Dose | Price | 3-Day Protocol | 5-Day Protocol | 7-Day Protocol |
250mg | $240 | $630 | $1,050 | $1470 |
500mg | $470 | $1,234 | $2,056 | $2,879 |
750mg | $620 | $1,628 | $2,713 | $3,798 |
The NAD+ protocol prices shown above have already been discounted by 12.5%.
Why 2.5 - 5 Hours Infusion is Better for Intracellular Uptake of NAD+
Dr. Ross Grant's research suggests that a slow infusion of NAD+ over 2.5 to 5 hours is more beneficial for intracellular uptake. The reasons include:
Gradual Cellular Absorption:
A slow infusion allows NAD+ to be gradually absorbed by cells, ensuring that it effectively enters the intracellular environment where it is needed for metabolic processes.
Rapid infusions can overwhelm the cells, leading to inefficient uptake and potential wastage of the molecule.
Sustained Release:
The extended infusion time provides a sustained release of NAD+ into the bloodstream, allowing for continuous availability to cells over a longer period. This helps maintain stable intracellular levels, enhancing the therapeutic effects.
Minimized Side Effects:
Slower administration reduces the risk of adverse side effects such as nausea, flushing, and gastrointestinal discomfort, which are more common with rapid infusions.
Why Fast Push Isn't Optimal
Dr. Grant's research highlights several reasons why a fast push of NAD+ is not optimal:
Inadequate Cellular Uptake:
Rapid administration can lead to a spike in NAD+ levels in the bloodstream, but this does not translate to effective intracellular uptake. The cells may not be able to absorb NAD+ quickly enough, resulting in inefficient use of the molecule.
Increased Risk of Side Effects:
Fast pushes can cause a range of side effects, including nausea, dizziness, flushing, and hypotension. These reactions occur because the body is unable to handle the sudden influx of NAD+.
Shortened Duration of Effect:
Rapid infusion leads to a quick rise and fall in NAD+ levels, which may not provide the sustained benefits needed for therapeutic effects. Slow infusion ensures prolonged exposure and better outcomes.
Potential for Overloading Systems:
High concentration over a short period can overload metabolic and detoxification pathways, potentially leading to stress on the liver and kidneys as they work to process the excess NAD+.
In conclusion, Dr. Ross Grant's research underscores the importance of proper dosing and administration techniques for NAD+ therapy. Slow infusions over 2.5 to 5 hours optimize intracellular uptake, minimize side effects, and enhance the therapeutic benefits of NAD+, making it a more effective approach compared to fast pushes.