Belle's standard compounded GLP-1 medications include added vitamins. Tirzepatide is compounded with vitamin B6, and semaglutide is compounded with vitamin B12 (methylcobalamin). These vitamins are commonly used in compounded formulations and do not change the safety, effectiveness, or intended use of your medication.
Patients with a B vitamin allergy or sensitivity can request our additive-free formulation. See Can I get compounded GLP-1 without B vitamins or other additives? for details.
Tirzepatide + B6: Vitamin B6 supports protein metabolism, mood regulation, immune function, and may help reduce nausea. The solution appears clear or slightly yellow.
Semaglutide + B12: Vitamin B12 supports red blood cell formation, nerve function, and energy. The solution appears pink or red due to the color of B12.
Good to know: Both medications use only the base form of the active ingredient (not salt forms) and are produced by FDA-registered compounding pharmacies.
Reading Your Vial Label
Because your medication is compounded with a vitamin, the vial label lists two active ingredients. Here's how to read it:
Tirzepatide + B6 (Pyridoxine HCl):
The label shows two separate lines — tirzepatide content and B6 content. Example: "60 mg/3 mL (20 mg/mL)" is the tirzepatide, "30 mg/3 mL (10 mg/mL)" is the B6. Use the tirzepatide line for dosing.
Concentration | Vial Size | Total Tirzepatide | Total B6 |
10 mg/mL | 1 mL | 10 mg | 10 mg |
10 mg/mL | 3 mL | 30 mg | 30 mg |
20 mg/mL | 2 mL | 40 mg | 20 mg |
20 mg/mL | 3 mL | 60 mg | 30 mg |
Semaglutide + B12 (Methylcobalamin):
The label shows a combined notation. Example: "2.5/0.5/mg/mL (10mg/2mg/4mL)" means 2.5 mg semaglutide + 0.5 mg B12 per mL. Use the first number for dosing.
Concentration | Vial Size | Total Semaglutide | Total B12 |
1 mg/mL | 1 mL | 1 mg | 0.5 mg |
2.5 mg/mL | 1 mL | 2.5 mg | 0.5 mg |
2.5 mg/mL | 2 mL | 5 mg | 1 mg |
2.5 mg/mL | 3 mL | 7.5 mg | 1.5 mg |
2.5 mg/mL | 4 mL | 10 mg | 2 mg |
For both medications, only the first number matters for dosing. The vitamin content does not change your injection volume. If you're unsure how many units to draw, see How do I convert units to milligrams for my dose? or use the Dosage Calculator.