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Creating New Plate Types in Synthace Builder

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Creating New Labware (Plate Types) in Synthace

This guide walks you through how to create and configure new labware (plate types) in the Synthace platform. Properly defining plate types ensures accurate workflow simulation and smooth integration with automation hardware.


Overview

Plate types define the physical characteristics of labware used in your workflows. These definitions are critical for:

  • Selecting labware in the Workflow Builder

  • Simulating liquid handling steps accurately

  • Integrating with supported automation systems (e.g. Hamilton or Tecan devices)


How to Create a New Plate Type

  1. From the Home page, navigate to Inventory

  2. Open the Plate Types Library

  3. Click Create New Plate Type

You can either:

  • Create a plate from scratch, or

  • Copy and modify an existing plate (recommended)


Key Fields and How to Fill Them

1. Plate Name

  • Used when selecting labware in workflows

  • Should be clear, descriptive, and unique

Example:
96 Well Flat Bottom Plate - Brand X


2. Plate Type Identifier

  • Must be unique across your system

  • Critical for integration with automation platforms

Important:

  • For Hamilton devices: this must match the name in your VENUS .RAC files

  • For EvoWare / Fluent Control: this links to manufacturer and part number values


3. Manufacturer and Part Number

  • Required fields

  • Must match the labware definition in your automation software

These values ensure Synthace can correctly map digital labware to physical hardware.


4. Plate Layout

Define the structure of the plate:

  • Well-based vs Column-based

    • Most plates are well-based

  • Number of rows and columns

    • Example:

      • 96-well plate → 8 rows × 12 columns

  • Well spacing and offsets

    • Defines physical positioning of wells

  • Plate dimensions

    • Overall size of the plate


5. Well Properties

Specify physical characteristics of each well:

  • Bottom shape:

    • Flat

    • V-bottom

    • U-bottom

  • Well shape:

    • Circular

    • Square (common)

    • Other


6. Volume Parameters (Critical)

These are the most important settings for workflow simulation:

  • Maximum Volume

    • The total capacity of each well

  • Residual Volume (Dead Volume)

    • The volume that cannot be aspirated

These values are used by the Workflow Builder to:

  • Prevent overfilling

  • Ensure accurate liquid handling simulation


Recommended Approach: Copy Existing Plates

Instead of creating from scratch:

  1. Find a similar plate in your library

  2. Duplicate it

  3. Update the following fields:

    • Plate name

    • Plate type identifier

    • Manufacturer

    • Part number

    • Volume parameters (if needed)

This approach:

  • Saves time

  • Reduces configuration errors

  • Ensures consistency


Summary of Critical Requirements

When creating a plate type, always ensure:

  • Plate name is clear and unique

  • Plate type identifier is unique and correctly mapped

  • Manufacturer and part number match automation software

  • Rows and columns reflect the real plate format

  • Maximum and residual volumes are accurate


Next Steps

Once your plate type is created:

  • It will be available in the Workflow Builder

  • You can use it in simulations and protocol design


If you encounter issues or are unsure about any parameters, contact your system administrator or Synthace support.

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