Mild tenderness after an injection is common, especially when you're starting out. Here's how to manage irritation depending on your injection method.
Subcutaneous (SubQ) Injections
Common symptoms: Mild redness, swelling, or itching at the injection site.
Recommendations:
Rotate injection sites each time to avoid overusing one area.
Inject slowly to reduce pressure under the skin.
Keep the needle steady while injecting to avoid tissue damage.
Use a new, sharp needle each time.
Intramuscular (IM) Injections
Common symptoms: Muscle tenderness, slight bruising, or tightness.
Recommendations:
Inject slowly to allow the muscle to absorb the fluid better.
Choose a relaxed muscle (e.g. glutes) and avoid injecting into tense or sore muscles.
Minimise needle movement during injection—enter at a steady angle and avoid repositioning once inserted.
Apply gentle pressure or a cold compress after injecting if soreness occurs.
When to Be Concerned
Most mild irritation will resolve within 1–3 days. However, check the site daily and take action if:
Redness, pain, or swelling lasts longer than 7 days
The area becomes hot, hard, or increasingly painful
You see pus, streaking redness, or experience fever
These could be signs of infection. Contact your prescribing doctor through your patient portal, or seek medical care if you're unsure.
Note: Always follow your injection training instructions and consult your doctor if injection issues continue.