Manual sequences allow you to set up sequences where you'd like to contact a group of people, but perhaps there is not a trigger available. The most common use for these sequences are things like "Challenges" and "Resets" where your members are getting drip-fed content over a period of time.
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This video shows you how to create a "Reset" sequence to send to your members where each week they receive a new workout.

When you've created a manual enrolment sequence, you can now bulk-enrol members by clicking the 3 dots at the end of the item line, then selecting bulk-enrol:

This allows you to choose statuses, or reports, to enrol your contacts in bulk into manual enrolment sequences:

Please note that only sequences with the Manual Enrolment trigger have the ability for bulk-enrolment. Any other sequences will trigger based on the sequence trigger set.