Occasional nausea or vomiting can happen on GLP-1 medications, especially in the first few weeks. If you vomit shortly after your injection, you may wonder if the medication still worked or if you need to re-dose.
Key Points
GLP-1 injections are absorbed slowly under the skin, not through the stomach.
Once injected, the medication enters your bloodstream over time—vomiting does not remove the dose.
You do not need to take another dose, even if vomiting occurs shortly after the injection.
What to Do
Do not re-inject or take another dose. You have still absorbed the medication.
Hydrate—sip small amounts of water or electrolyte drinks to prevent dehydration.
Eat light—stick to bland, low-fat meals for the next 12–24 hours (e.g. rice, toast, broth).
Rest and monitor—most nausea or vomiting settles within hours.
Preventing Future Nausea or Vomiting
Avoid large or fatty meals around the time of your dose.
Eat smaller meals throughout the day.
Avoid lying down immediately after eating.
Speak with your doctor if nausea is ongoing—they may delay your next dose increase or recommend support options.
When to Seek Medical Advice
Contact your doctor if:
Vomiting continues for more than 24 hours
You can’t keep fluids down
You feel dizzy, faint, or dehydrated
Vomiting happens with severe abdominal pain (this may indicate a more serious issue like pancreatitis)
Vomiting after a dose can be unpleasant, but you still absorbed your medication. Do not take an extra dose. Focus on staying hydrated, eating lightly, and monitoring your symptoms.
If you’re unsure, contact your prescribing doctor through the patient portal.