Constipation is a common and expected side effect of GLP-1 medications. These medications slow digestion, which can affect how often and how easily you pass bowel movements.
What to Expect
Bowel movements may become less frequent, harder, or more difficult to pass.
You might feel bloated or have a sense of incomplete emptying.
This is most common in the first few weeks of treatment or after a dose increase.
Why It Happens
GLP-1 medications delay stomach emptying and slow intestinal movement. Combined with a lower food intake and reduced fluid consumption (common due to appetite suppression), these factors can lead to constipation.
How to Reduce Constipation
Increase water intake: Aim for at least 2–3L per day.
Eat more fibre: Include vegetables, fruits, oats, and whole grains.
Move daily: Even light walking supports gut motility.
Avoid constipating foods: Limit cheese, processed snacks, and refined carbs.
Magnesium: Over-the-counter magnesium citrate or magnesium oxide can help gently draw water into the bowel.
Fibre supplements: Products like psyllium husk can support regularity.
When to Contact Your Doctor
No bowel movement for more than 5 days.
Severe abdominal pain or bloating.
Nausea, vomiting, or signs of bowel blockage.
Constipation usually improves as your body adjusts. Staying hydrated and active makes a major difference. If symptoms persist, speak with your doctor to explore simple treatment options.