Learn the core elements
Learn how to use the core elements in Synthace.
69 articles
Core elements tutorialsLearn how to use the Core Elements in Synthace.
Control Liquid Transfer Limits Using Liquid Selection CriteriaSet min/max volume limits for liquids, or groups of liquids, to influence stock generation, while taking into account device constraints.
Define liquids and plates
Provide Synthace with a definition of your samples, buffers and reagents in one simple interface
Define a set of liquids and platesCore elements tutorial 1.0
Define a set of liquids and plates from a table or fileCore elements tutorial 1.1
Guided Walkthrough: Defining multiple liquids through the table editorTake a quick tour through the table editor
Define a set of liquids from parametersCore elements tutorial 1.2
Allocate a set of predefined liquids to a plate from parametersCore elements tutorial 1.3
Define a set of liquids and plates from a previous simulationCore elements tutorial 1.4
Input PlatesEvery liquid must start in an input plate that is defined either by you or automatically by Synthace.
Allocate liquids to plates and wells
Learn how to control the location of liquids in plates, troughs and tubes
Describe plate and well layout preferencesCore elements tutorial 2.0
Define a plate set to which Synthace can allocate some liquidsCore elements tutorial 2.1
Allocate some liquids to specific wellsCore elements tutorial 2.2
Allocate different liquids to different plate setsCore elements tutorial 2.3
Control the orientation of well allocationCore elements tutorial 2.4
Reuse plate sets in multiple elementsCore elements tutorial 2.5
Scale transfers to multiple platesCore elements tutorial 2.6
Dilute
Easily and flexibly dilute your samples, by factor or concentration
DiluteCore elements tutorial 3.0
Serially dilute a set of substrates for an enzyme assay into a new plateCore elements tutorial 3.1
Serially dilute a standard across a specified concentration rangeCore elements tutorial 3.2
Serially dilute an enzyme to specific concentrationsCore elements tutorial 3.3
Direct dilution of a liquid to a specific concentrationCore elements tutorial 3.4
Dilute in placeCore elements tutorial 3.5
Deferred Transfers: DiluteThis article goes over how to use the deferred transfers functionality when applying it to the Dilute element.
Choose how to group your replicates and dilutions.Specify how you want Synthace to allocate dilutions and their replicates.
Normalize
Save time on tedious calculations. Learn how to normalize samples
NormalizeCore elements tutorial 4.0
Normalize samples by concentration to a new plateCore elements tutorial 4.1
Normalize samples by concentration in placeCore elements tutorial 4.2
Normalize samples by volume in placeCore elements tutorial 4.3
Make mixtures
Learn how to prepare mixtures, mastermixes or reactions
Make mixturesCore elements tutorial 5.0
Make mixtures by volume orderCore elements tutorial 5.1
Make mixtures by liquid orderCore elements tutorial 5.2
Define mixtures through a plate-based interfaceLearn how the plate-based mixtures interface can be used with the Make Mixtures and Mix Onto elements
Define mixtures through a plate-based interface using Descriptive Mode
Define mixtures through a plate-based interface using Combinatorial Mode
Make Mixtures by liquid selection using deferred transfer with Mix OntoOptimize liquid ordering using multiple execution modes, or delaying addition of specific liquids with deferred transfers.
Mix onto
Dispense any number of liquids onto an existing plate with Mix Onto
Mix ontoCore elements tutorial 6.0
Mix all onto allCore elements tutorial 6.1
Mix in orderCore elements tutorial 6.2
Mix by compositionCore elements tutorial 6.3
Select liquids based on tagsCore elements tutorial 8.2
Stamp Liquids
Use Stamp Liquids to transfer liquids while keeping layouts intact—supports manual use, 96-heads, and autoscaling with Calculate Value.
Introducing Stamp LiquidsUse Stamp Liquids to transfer liquids while keeping layouts intact—supports manual use, 96-heads, and autoscaling with Calculate Value.
Using Stamp Liquids in SynthaceUse Stamp Liquids to transfer liquids while keeping layouts intact—supports manual use, 96-heads, and autoscaling with Calculate Value.
Select
Apply logical criteria to your automation process with Select - The Most Powerful Element of them all!
Select some liquids based on their propertiesCore elements tutorial 8.0
Select liquids based on concentrationCore elements tutorial 8.1
Use unselected liquidsCore elements tutorial 8.3
Combing small workflow units
Develop beyond the basics, and learn how the modularity of the elements make complex process easy
Combine smaller workflow unitsCore elements tutorial 9.0
Select liquids based on concentration and normalize to a new plateCore elements tutorial 9.1
Basic quantification assays
Dive into some real-world examples. Learn how to build common bioloigical assays with ease
Basic quantification assaysCore elements tutorial 10.0
Building a basic quantification assay workflowCore elements tutorial 10.1
Basic quantification assay with execution orderCore elements tutorial 10.2
Bradford AssayCore elements tutorial 10.3
PicoGreen AssayCore elements tutorial 10.4
Advanced assays
Take your workflow building to the next level
Bradford Assay - scalingCore elements tutorial 11.1
Mycoplasma assayCore elements tutorial 11.2
Build flexible, scalable workflows with the core elements
Master the Synthace elements, with powerful, flexible and adaptible workflows
Build flexible, scalable workflows with the core elementsCore elements tutorial 12.0
Cherry-pick samples based on concentration for normalizationCore elements tutorial 12.1
Mix liquids based on sample metadataCore elements tutorial 12.2
Utilizing Plate Hotels on Your Liquid HandlerMaximize the useable deck space on your liquid handler by leveraging plate hotels.
Use of metadata for dilutions and mixingCore elements tutorial 12.3
Using Move Plates and Move Plates Back ElementsUse these elements to instruct a liquid handler to plates to a different deck region and to return plate to its original location.
Technical notes
See the elements in action and dive into the details of automation with Synthace's Lab team
AliquotCore elements technical notes
DiluteCore elements technical notes
Make mixturesCore elements technical notes
Mix ontoCore elements technical notes
NormalizeCore elements technical notes
SelectCore elements technical notes